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Randi Eikeland

Randi Eikeland

Professor

Department of Health and Nursing Sciences >

 

+47 37 23 34 50

+47 908 80 246

Office:
C4036 ( Jon Lilletuns vei 9, Grimstad )
Office hours:
torsdager 09-15

Work experience

1997-1999 Consultant neurology Department of neurology, Aust-Agder Hospital

1999-2000Consultant Department of neurosurgery, University hospital of Oslo

2000-2019 Consultant Department of neurology, Sørlandet Hospital 

2019-2020 Neurologist Department of pediatrics habilitation, Sørlandet Hospital

2019-202 Neurologist Competence Center for children with prenatal alcohol/drug exposure

2020-2021 Infectious diseases control consultant Sørlandet Hospital 

2021-2023 Associated professor at the  University of Agder,Institut for health and nursing science

2014-DD Leader of The Norwegian National Advisory Unit on Tick-borne diseases, Sørlandet Hospital 

2015-DD Research consultant Sørlandet Hospital 

2023-DD  Professor at the  University of Agder, Institute for health and nursing science

Selected publications

Eikeland Randi (2012) European neuroborreliosis-long term follow up. University of Bergen, Faculty of Medisin. ISBN 978-82-308-2029-2

Ljøstad U, Skogvoll E, Eikeland R, Midgard R, Skarpaas T, Berg A, Mygland A. Oral doxycycline versus intravenous ceftriaxone for European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blind, randomised trial. Lancet Neurol. 2008 Aug;7(8):690-5. doi: 10.1016/S1474-4422(08)70119-4.

Quist-Paulsen E, Ormaasen V, Kran AB, Dunlop O, Ueland PM, Ueland T, Eikeland R, Aukrust P, Nordenmark TH. Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning. Sci Rep. 2019 Nov 6;9(1):16158. doi: 10.1038/s41598-019-52570-2.

Eikeland R, Ljøstad U, Helgeland G, Sand G, Flemmen HØ, Bø MH, Nordaa L, Owe JF, Mygland Å, Lorentzen ÅR. Patient-reported outcome after treatment for definite Lyme neuroborreliosis. Brain Behav. 2020 Apr;10(4):e01595. doi: 10.1002/brb3.1595.

Knudtzen FC, Eikeland R, Bremell D, Quist-Paulsen E, Johansen I, Solheim AM, Skarphedinsson. Lyme neuroborreliosis with encephalitis, a systematic literature review and a Scandinavian cohort study.Clin Microbiol Infect. 2021 PMID: 34768019.

Andreassen S, Lindland ES, Solheim AM, Beyer MK, Ljøstad U, Mygland Å, Lorentzen ÅR, Reiso H, Harbo HF, Løhaugen GCC, Eikeland R. Cognitive Function, fatigue and Fazekas score in patients with acute neuroborreliosis. Ticks Tick Borne Dis 2021 doi: 10.1016/j.ttbdis.2021.101678.

Andreassen S, Solheim AM, Ljøstad U, Mygland Å D, Lorentzen ÅR, Reiso H, Beyer MK, Harbo HF, Løhaugen GCC, Eikeland R. Cognitive function in patients with neuroborreliosis: A prospective cohort study from the acute phase to 12 months post treatment Brain and behaviour 2022 Doi: 10.1002/brb3.2608.

Halperin J, Eikeland R, Branda JA, Dersch R. Lyme neuroborreliosis, known knowns and known unknowns. Brain 2022 DOI: 10.1093/brain/awac206.

Solheim AM, Lorentzen ÅR, Dahlberg AO, Flemmen HØ, Brune S, Forselv KJN, Pripp AH, Bø MH, Eikeland R, Reiso H, Mygland Å, Ljøstad U.Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blinded, randomised and placebo-controlled trial J Neurol Neurosurg Psychiatry 2022 Jul 27;93(11):1222-1228. doi: 10.1136/jnnp-2022-329.

Sarjomaa M, Diep LM, Zhang C, Tveten Y, Reiso H, Thilesen C, Nordbø SA, Berg KK, Aaberge I, Pearce N, Kersten H, Vandenbroucke JP, Eikeland R, Fell AKM. SARS-CoV-2 antibody persistence after five and twelve months: A cohort study from South-Eastern Norway.2022 PLoS One. DOI: 10.1371/journal.pone.0264667.

Andreassen S, Lindland EMS, Beyer MK, Solheim AM, Ljøstad U, Mygland Å, Lorentzen ÅR, Reiso H, Bjuland KJ, Pripp AH, Harbo HF, Løhaugen GCC, Eikeland R. Assessment of cognitive function, structural brain changes and fatigue 6 months after treatment of neuroborreliosisJ Neurol. 2023 Mar;270(3):1430-1438. doi: 10.1007/s00415-022-11463-7.

Akhvlediani T, Bernard-Valnet R, Diaz R, Eikeland R, Pfausler B, Sellner J. Neurological side effects and drug interactions of antiviral compounds against SARS-CoV-2 European Journal of Neurol. 2023 Aug EJoN-23-1206.R1

Scientific publications

  • Lindland, Elisabeth S.; Røvang, Martin S.; Solheim, Anne Marit; Andreassen, Silje; Skarstein, Ingerid; Dareez, Nazeer; MacIntosh, Bradley J.; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse; Bos, Steffan D.; Ulvestad, Elling; Reiso, Harald; Lorentzen, Åslaug R.; Harbo, Hanne F.; Bjørnerud, Atle; Beyer, Mona K. (2024). Are white matter hyperintensities associated with neuroborreliosis? The answer is twofold. Neuroradiology. ISSN: 0028-3940. doi:10.1007/s00234-024-03482-0.
  • Solheim, Anne Marit; Skarstein, Ingerid; Quarsten, Hanne; Lorentzen, Åslaug Rudjord; Berg-Hansen, Pål; Eikeland, Randi; Reiso, Harald; Mygland, Åse Daasvand; Ljøstad, Unn (2024). Clinical and laboratory characteristics during a 1-year follow-up in European Lyme neuroborreliosis: A prospective cohort study. European Journal of Neurology. ISSN: 1351-5101. doi:10.1111/ene.16487.
  • Skudal, Hilde Kristin; Lorentzen, Åslaug Rudjord; Stenstad, Tore; Paulsen, Else Quist; Egeland, Jens; Fevang, Børre; Jaioun, Keson; Hansen, Bjørn Åsheim; Solheim, Anne Marit; Tveten, Yngvar; Veje, Malin; Eikeland, Randi; Kersten, Hege (2024). Clinical characteristics and factors affecting disease severity in hospitalized tick-borne encephalitis patients in Norway from 2018 to 2022. European Journal of Clinical Microbiology and Infectious Diseases. ISSN: 0934-9723. 43 (7). s 1355 - 1366. doi:10.1007/s10096-024-04855-2.
  • Quarsten, Hanne; Andreassen, Åshild Kristine; Paulsen, Katrine Mørk; Diekmann, Maria Juul; Eikeland, Randi; Helleren, Rita; Bergström, Tomas; Noraas, Sølvi; Lorentzen, Åslaug Rudjord (2024). No detection of tick-borne encephalitis virus RNA in blood, urine or saliva of hospitalised immunocompetent tick-borne encephalitis patients. PLOS ONE. ISSN: 1932-6203. 19 (6). doi:10.1371/journal.pone.0305603.
  • Sarjomaa, Marjut Anneli; Zhang, Chi; Tveten, Yngvar; Kersten, Hege; Reiso, Harald; Eikeland, Randi; Kongerud, Johny Steinar; Berg, Kristine Karlsrud; Thilesen, Carina; Nordbø, Svein Arne; Aaberge, Ingeborg S.; Vandenbroucke, Jan; Pearce, Neil; Fell, Anne Kristin M. (2024). Risk factors for SARS-CoV-2 infection: A test-negative case-control study with additional population controls in Norway. BMJ Open. ISSN: 2044-6055. 14 (1). s 1 - 11. doi:10.1136/bmjopen-2023-073766.
  • Skarstein, Ingerid; Ulvestad, Elling; Solheim, Anne Marit; Vedeler, Christian; Ljøstad, Unn; Mygland, Åse; Eikeland, Randi; Reiso, Harald; Lorentzen, Åslaug Rudjord; Bos-Haugen, Steffan Daniel (2024). Serum neurofilament light chain associates with symptom burden in Lyme neuroborreliosis patients: a longitudinal cohort study from Norway. Journal of Neurology. ISSN: 0340-5354. 271s 2768 - 2775. doi:10.1007/s00415-024-12237-z.
  • Eikeland, Randi; Henningsson, Anna J.; Lebech, Anne-Mette; Kerlefsen, Yvonne; Mavin, Sally; Vrijlandt, Amber; Hovius, Joppe W.; Lernout, Tinne; Lim, Chin; Dobler, Gerhard; Fingerle, Volker; Gynthersen, Rosa M.; Lindgren, Per-Eric; Reiso, Harald (2024). Tick-borne diseases in the North Sea region–A comprehensive overview and recommendations for diagnostics and treatment. Ticks and Tick-borne Diseases. ISSN: 1877-959X. 15 (2). doi:10.1016/j.ttbdis.2023.102306.
  • Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Andreassen, Silje; Bugge, Robin Antony Birkeland; Eikeland, Randi; Reiso, Harald; Lorentzen, Åslaug Rudjord; Harbo, Hanne-Cathrin Flinstad; Beyer, Mona Kristiansen; Bjørnerud, Atle (2023). Dynamic contrast-enhanced MRI shows altered blood–brain barrier function of deep gray matter structures in neuroborreliosis: a case–control study. European Radiology Experimental. 7 (1). doi:10.1186/s41747-023-00365-6.
  • Tjernberg, Ivar; Lager, Malin; Jensen, Guro Furset; Eikeland, Randi; Nyman, Dag; Brudin, Lars; Henningsson, Anna J. (2023). Identification of potential biomarkers in active Lyme borreliosis. PLOS ONE. ISSN: 1932-6203. 18 (6). doi:10.1371/journal.pone.0287586.
  • Bernardsjaw, Emilie; Gynthersen, Rosa; Bremell, Daniel; Mens, Helene; Stenør, Christian; Lorentzen, Åslaug Rudjord; Bodilsen, Jacob; Eikeland, Randi; Lebech, Anne-Mette (2022). Antibiotic therapy of neuroborreliosis: A survey among infectious disease specialists and neurologists in Norway, Sweden, and Denmark. Ticks and Tick-borne Diseases. ISSN: 1877-959X. 13 (6). doi:10.1016/j.ttbdis.2022.102051.
  • Andreassen, Silje; Lindland, Elisabeth Margrete Stokke; Beyer, Mona K.; Solheim, Anne Marit; Ljøstad, Unn; Mygland, Åse Daasvand; Lorentzen, Åslaug Rudjord; Reiso, Harald; Bjuland, Knut Jørgen; Pripp, Are Hugo; Harbo, Hanne-Cathrin Flinstad; Løhaugen, Gro; Eikeland, Randi (2022). Assessment of cognitive function, structural brain changes and fatigue 6 months after treatment of neuroborreliosis. Journal of Neurology. ISSN: 0340-5354. doi:10.1007/s00415-022-11463-7.
  • Andreassen, Silje; Solheim, Anne Marit; Ljøstad, Unn; Mygland, Åse Daasvand; Lorentzen, Åslaug Rudjord; Reiso, Harald; Beyer, Mona Kristiansen; Harbo, Hanne-Cathrin Flinstad; Løhaugen, Gro; Eikeland, Randi (2022). Cognitive function in patients with neuroborreliosis: A prospective cohort study from the acute phase to 12 months post treatment. Brain and Behavior. ISSN: 2162-3279. 12 (6). doi:10.1002/brb3.2608.
  • Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Dareez, Muhammad Nazeer; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse Daasvand; Reiso, Harald; Lorentzen, Åslaug Rudjord; Harbo, Hanne; Beyer, Mona Kristiansen (2022). Enhancement of cranial nerves in Lyme neuroborreliosis: incidence and correlation with clinical symptoms and prognosis. Neuroradiology. ISSN: 0028-3940. 64s 2323 - 2333. doi:10.1007/s00234-022-02957-2.
  • Sarjomaa, Marjut Anneli; Diep, Lien My; Zhang, Chi; Tveten, Yngvar; Reiso, Harald; Thilesen, Carina; Nordbø, Svein Arne; Berg, Kristine Karlsrud; Aaberge, Ingeborg Aase S.; Pearce, Neil; Kersten, Hege; Vandenbroucke, Jan Paul; Eikeland, Randi; Fell, Anne Kristin M. (2022). SARS-CoV-2 antibody persistence after five and twelve months: A cohort study from South-Eastern Norway. PLOS ONE. ISSN: 1932-6203. 17 (8). s 1 - 15. doi:10.1371/journal.pone.0264667.
  • Lie, Ingrid Anne; Kacar, Sezgi; Wesnes, Kristin; Brouwer, Iman; Kvistad, Silje Agnethe Stokke; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne-Cathrin Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Varhaug, Kristin Nielsen; Vedeler, Christian Alexander; Barkhof, Frederik; Teunissen, Charlotte E.; Bø, Lars; Torkildsen, Øivind Fredvik Grytten; Myhr, Kjell-Morten; Vrenken, Hugo (2022). Serum neurofilament as a predictor of 10-year grey matter atrophy and clinical disability in multiple sclerosis: a longitudinal study. Journal of Neurology, Neurosurgery and Psychiatry. ISSN: 0022-3050. 93 (8). s 849 - 857. doi:10.1136/jnnp-2021-328568.
  • Solheim, Anne Marit; Lorentzen, Åslaug Rudjord; Dahlberg, Audun Olav; Flemmen, Heidi Øyen; Brune, Synne; Forselv, Kristine Johanne Nordstrøm; Pripp, Are Hugo; Bø, Margrete Halvorsen; Eikeland, Randi; Reiso, Harald; Mygland, Åse Daasvand; Ljøstad, Unn (2022). Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blinded, randomised and placebo-controlled trial. Journal of Neurology, Neurosurgery and Psychiatry. ISSN: 0022-3050. 93 (11). s 1222 - 1228. doi:10.1136/jnnp-2022-329724.
  • Lie, Ingrid Anne; Wesnes, Kristin; Kvistad, Silje Agnethe Stokke; Brouwer, Iman; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne-Cathrin Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Barkhof, Frederik; Vrenken, Hugo; Myhr, Kjell-Morten; Bø, Lars; Torkildsen, Øivind (2022). The Effect of Smoking on Long-term Gray Matter Atrophy and Clinical Disability in Patients with Relapsing-Remitting Multiple Sclerosis. Neurology: Neuroimmunology and neuroinflammation. ISSN: 2332-7812. 9 (5). s 1 - 10. doi:10.1212/NXI.0000000000200008.
  • Andreassen, Silje; Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Beyer, Mona K.; Ljøstad, Unn; Mygland, Åse Daasvand; Lorentzen, Åslaug Rudjord; Reiso, Harald; Harbo, Hanne Flinstad; Løhaugen, Gro; Eikeland, Randi (2021). Cognitive function, fatigue and Fazekas score in patients with acute neuroborreliosis. Ticks and Tick-borne Diseases. ISSN: 1877-959X. 12 (3). s 1 - 5. doi:10.1016/j.ttbdis.2021.101678.
  • Wesnes, Kristin; Myhr, Kjell-Morten; Riise, Trond; Kvistad, Silje Agnethe Stokke; Torkildsen, Øivind; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne Flinstad; Kleveland, Grethe; Sørenes, Yvonne S.; Øksendal, Nina; Bjørnevik, Kjetil Lauvland (2021). Low vitamin D, but not tobacco use or high BMI, is associated with long-term disability progression in multiple sclerosis. Multiple Sclerosis and Related Disorders. ISSN: 2211-0348. 50:102801s 1 - 7. doi:10.1016/j.msard.2021.102801.
  • Eikeland, Randi; Ljøstad, Unn; Helgeland, Geir; Sand, Geir; Flemmen, Heidi Øyen; Bø, Margrete Halvorsen; Nordaa, Ludmila; Owe, Jone Furulund; Mygland, Åse; Lorentzen, Åslaug Rudjord (2020). Patient-reported outcome after treatment for definite Lyme neuroborreliosis. Brain and Behavior. ISSN: 2162-3279. 10 (4). s 1 - 7. doi:10.1002/brb3.1595.
  • Margos, Gabriele; Castillo-Ramírez, Santiago; Cutler, Sally; Dessau, Ram; Eikeland, Randi; Estrada-Peña, Agustin; Gofton, Alexander; Graña-Miraglia, Lucía; Hunfeld, Klaus-Peter; Krause, Andreas; Lienhard, Reto; Lindgren, Per-Eric; Oskam, Charlotte; Rudolf, Ivo; Schwartz, Ira; Sing, Andreas; Stevenson, Brian; Wormser, Gary P.; Fingerle, Volker (2020). Rejection of the name Borreliella and all proposed species comb. nov. placed therein. International Journal of Systematic and Evolutionary Microbiology. ISSN: 1466-5026. 70 (5). s 3577 - 3581. doi:10.1099/ijsem.0.004149.
  • Quist-Paulsen, Else; Ormaasen, Vidar; Kran, Anne-Marte Bakken; Dunlop, Oona Borghild; Ueland, Per Magne; Ueland, Thor; Eikeland, Randi; Aukrust, Pål; Nordenmark, Tonje Haug (2019). Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning. Scientific Reports. ISSN: 2045-2322. 9doi:10.1038/s41598-019-52570-2.
  • Smaradottir, Berglind; Eikeland, Randi; Reiso, Harald; Fensli, Rune Werner (2018). User-centered design of a national medical registry for tick-borne diseases. Advances in Intelligent Systems and Computing. ISSN: 2194-5357. 779s 99 - 108. doi:10.1007/978-3-319-94373-2_11.
  • Forselv, Kristine Johanne Nordstrøm; Lorentzen, Åslaug Rudjord; Ljøstad, Unn; Mygland, Åse; Eikeland, Randi; Kjelland, Vivian; Noraas, Sølvi; Quarsten, Hanne (2017). Does more favourable handling of the cerebrospinal fluid increase the diagnostic sensitivity of Borrelia burgdorferi sensu lato-specific PCR in Lyme neuroborreliosis?. Infectious Diseases. ISSN: 2374-4235. 50 (4). s 297 - 302. doi:10.1080/23744235.2017.1399315.
  • Lorentzen, Åslaug Rudjord; Forselv, Kristine Johanne Nordstrøm; Helgeland, Geir; Salvesen, Rigmor Elisabeth; Sand, Geir; Flemmen, Heidi Øyen; Bø, Margrete Halvorsen; Nordaa, Ludmila; Roos, Anna Katharina; Jim, Marion W.; Owe, Jone Furulund; Nyquist, Kaja Beate; Schüler, Stephan; Eikeland, Randi; Mygland, Åse; Ljøstad, Unn (2017). Lyme neuroborreliosis: do we treat according to guidelines?. Journal of Neurology. ISSN: 0340-5354. 264 (7). s 1506 - 1510. doi:10.1007/s00415-017-8559-z.
  • Roaldsnes, Erlend; Eikeland, Randi; Berild, Dag (2017). Lyme-nevroborreliose ved uspesifikke nevrologiske symptomer. Tidsskrift for Den norske legeforening. ISSN: 0029-2001. 137 (2). s 101 - 104. doi:10.4045/tidsskr.15.1115.
  • Fell, Anne Kristin Møller; Eikeland, Randi; Aaseth, Jan (2016). En kvinne i 30-årene med hoste, tremor, uro og synsforstyrrelser. Tidsskrift for Den norske legeforening. ISSN: 0029-2001. 136 (14-15). s 1233 - 1235. doi:10.4045/tidsskr.15.0998.
  • Eikeland, Randi; Mygland, Åse; Herlofson, Karen; Ljøstad, Unn (2013). Risk factors for a non-favorable outcome after treated European neuroborreliosis. Acta Neurologica Scandinavica. ISSN: 0001-6314. 127 (3). s 154 - 160. doi:10.1111/j.1600-0404.2012.01690.x.
  • Eikeland, Randi; Ljøstad, Unn; Mygland, Åse; Herlofson, Karen; Løhaugen, Gro (2012). European neuroborreliosis: neuropsychological findings 30 months post-treatment. European Journal of Neurology. ISSN: 1351-5101. 19 (3). s 480 - 487. doi:10.1111/j.1468-1331.2011.03563.x.
  • Juvkam, Kari Hilde; Eikeland, Randi (2011). En mann med akutt innsettende smerter i høre hofte og lår. Tidsskrift for Den norske legeforening. ISSN: 0029-2001. 131 (9-10). s 959 - 961. doi:10.4045/tidsskr.09.0750.
  • Eikeland, Randi; Mygland, Åse; Herlofson, Karen; Ljøstad, Unn (2011). European neuroborreliosis: quality of life 30 months after treatment. Acta Neurologica Scandinavica. ISSN: 0001-6314. 124 (5). s 349 - 354. doi:10.1111/j.1600-0404.2010.01482.x.
  • Riise, Trond; Kirkeleit, Jorunn; Aarseth, Jan Harald; Farbu, Elisabeth; Midgard, Rune; Mygland, Åse; Eikeland, Randi; Mørland, Tore; Telstad, Wenche; Førland, Per Tore; Myhr, Kjell-Morten (2011). Risk of MS is not associated with exposure to crude oil, but increases with low level of education. Multiple Sclerosis. ISSN: 1352-4585. 17 (7). s 780 - 787. doi:10.1177/1352458510397686.
  • Ljøstad, Unn; Skogvoll, Eirik; Eikeland, Randi; Midgard, Rune; Skarpaas, Tone; Skarpaas, Tone; Berg, Åse; Mygland, Åse (2008). Oral doxycycline versus intravenous ceftriaxone for European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blind, randomised trial. Lancet Neurology. ISSN: 1474-4422. 7s 690 - 695. doi:10.1016/S1474-4422(08)70119-4.
  • Reiso, Harald; Eikeland, Randi; Kerlefsen, Yvonne; Omnes, Steinar; Ludvigsen, Ann-Elisabeth (2024). TickCheck-a web based application for assesing skin rashes after tick-bites.
  • Bos-Haugen, Steffan Daniel; Skarstein, Ingerid; Eikeland, Randi; Solheim, Anne Marit (2024). Serum neurofilament light chain associates with disease activity in Lyme neuroborreliosis patients-a longitudinal sohort study from Norway.
  • Eikeland, Randi (2024). Flåttsykdommer i Norge.
  • Eikeland, Randi (2024). Flått og flåttbårne sydkommer.
  • Eikeland, Randi (2024). Brukerorientert innovasjon på et norsk sykehus, veien til en web basert billedtjeneste som skal vurdere ditt utslett etter flåttbitt.
  • Eikeland, Randi (2024). Infeksjonskurs for indremedisinere Borrelia og TBE.
  • Eikeland, Randi (2024). Tick-Borne Encephalitis and Lyme Borreliosis, common and rare clinical presentations.

Sectors

Last changed: 20.12.2023 13:12