My current research follows two main themes: (a) studying mitochondrial viability and targeted nutritional interventions to tackle impaired bioenergetics in health and disease, and (b) analyzing population health metrics in chronic cardiometabolic diseases. My research expertise and experience include pre-clinical and clinical development of mitochondria-related nutraceuticals, randomized controlled trials with nutritional interventions, pharmacokinetics of dietary supplements, tissue-specific metabolic assessment and translation, and clinical physiology.
Nutritional neuroscience
Bioenergetics / Energy Metabolism
Nutraceuticals
Randomized controlled trials
Mitochondria
Molecular nutrition
Creatine
ERN 205
ERN 211
Sergej Ostojic is a member of international research networks in population health, including European Childhood Obesity Surveillance Initiative (World Health Organization), NCD Risk Factor Collaboration (Imperial College London), and Global Burden of Disease (University of Washington).
List of of recent scientific projects registered at ClinicalTrials.gov is availlable here
Top 10 papers in 2021
Ostojic SM. Guanidinoacetic acid loading for improved location-specific brain creatine. Clinical Nutrition, 2021;40(1):324-326. DOI: 10.1016/j.clnu.2020.05.003.
Ostojic SM, Forbes SC. Creatine, a conditionally essential nutrient: building the case. Advances in Nutrition, 2021. DOI: 10.1093/advances/nmab111.
Ostojic SM. Hydrogen-rich water as a modulator of gut microbiota? Journal of Functional Foods, 2021;78:104360. DOI: 10.1016/j.jff.2021.104360.
Ostojic SM. Hydrogen as a potential therapeutics in obesity: targeting the brain. Trends in Endocrinology and Metabolism, 2021;32(4):191-193. DOI: 10.1016/j.tem.2021.01.002.
Korovljev D, Stajer V, Ostojic SM. Relationship between dietary creatine and growth indicators in children and adolescents aged 2–19 years: a cross-sectional study. Nutrients. 2021;13(3):1027. DOI: 10.3390/nu13031027.
Ostojic SM. Stimulation of CT1 function: from Klotho protein to ammonia and beyond. Frontiers in Nutrition, 2021;8:660021. DOI: 10.3389/fnut.2021.660021.
Ostojic SM. Creatine as a food supplement for the general population. Journal of Functional Foods, 2021. DOI: 10.1016/j.jff.2021.104568.
Korovljev D, Todorovic N, Stajer V, Ostojic SM. Temporal trends in dietary creatine intake from 1999 to 2018: an ecological study with 89,161 participants. Journal of the International Society of Sport Nutrition, 2021;18:53. DOI: 10.1186/s12970-021-00453-1.
NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1,201 population-representative studies with 104 million participants. Lancet, 2021. DOI: 10.1016/S0140-6736(21)01330-1.
GBD 2019 Collaborators. Global mortality from dementia: Application of a new method and results from the Global Burden of Disease Study 2019. Alzheimers Dement (N Y). 2021;7(1):e12200. DOI: 10.1002/trc2.12200.
Sergej Ostojic is Associate Editor of the scientific journals Frontiers in Physiology and Research in Sports Medicine, Review Editor for Frontiers in Pharmacology, Frontiers in Nutrition and International Journal of Public Health, Editorial Consultant for Current Topics in Nutraceutical Research, and Editorial Board member for Food Science and Nutrition and Journal of Functional Foods.
He is also a member of the American College of Physicians, the American Society for Nutrition, the American Physiological Society, the Nutrition Society, International Society for Cerebral Blood Flow and Metabolism, and Mitochondrial Medicine Society.
Last changed: 15.12.2021 10:12